lateral cerebral ventricle injection

Objective:To study the expression of ferroportin 1(FP1)、ceruloplasmin(CP)and divalent metal transporter 1(DMT1)and their mRNA in cerebral cortex and hippocampus regulated by lateral cerebral ventricle injection of the lipopolysaccharide(LPS).
目的:研究大鼠侧脑室注射脂多糖对脑皮质和海马膜铁转运蛋白1(ferroportin,FP1)、铜蓝蛋白(ceruloplasmin,CP)和二价金属离子转运体1(divalent metal transporter 1,DMT1)及此三种蛋白mRNA表达的变化,进而了解脑部炎症引起的脑铁代谢紊乱及其导致的神经退行性疾病,为临床诊断和治疗神经退行性疾病提供理论依据。

医药科学